Diana Bishop, a student of history and hesitant witch, out of the blue finds an entranced original copy in Oxford's Bodleian Library. This revelation drives her go into the universe of enchantment so as to disentangle the insider facts it holds about supernatural creatures. She is offered assistance by baffling geneticist and vampire, Matthew Clairmont. Notwithstanding a since a long time ago held question among witches and vampires, they structure a collusion and set out to secure the book and fathom the riddles concealed inside while evading dangers from the animal world.