Following a 200-year-old medication container found on a seaward wreck breaks in a high school young lady's palm, she is admitted to Princeton Plainsboro for indications firmly connected to smallpox. At the point when the Center for Disease Control's Dr. Dave Broda foundations a lockdown on the emergency clinic and suspends House's group's capacity to analyze, Masters is incredulous about Broda's determination and becomes persuaded that the patient is experiencing an alternate infection. The young lady's dad before long encounters comparative indications, and House is compelled to settle on an unsafe choice that places his own life in ...